Zofran (Ondansetron) Birth Defects

Zofran has been linked to certain birth defects when it is taken during the first trimester of pregnancy. Zofran is an antiemetic 5-HT3 receptor antagonist used to treat nausea and vomiting. The FDA initially approved Zofran (Ondansetron) for the treatment of chemotherapy induced nausea and vomiting. Later the FDA approved Zofran for post-operative nausea and vomiting but the drug was never approved for pregnancy induced nausea and vomiting. Nevertheless, GlaxoSmithKline actively and aggressively promoted the drug to OB/GYNs for the treatment of nausea and vomiting caused by pregnancy. GlaxoSmithKline allegedly misrepresented the safety of this drug when given during the first trimester, which is when most pregnant women experience nausea and vomiting. Studies have shown when Zofran is ingested during the first trimester it can cause congenital birth defects and cleft palate.

Litigation is currently pending in the US District Court of Massachusetts under In Re: Zofran (Ondansetron) Products Liability Litigation, MDL 2657. GSP attorney, Melissa Hague was appointed by the MDL judge, Judge Saylor, to serve on the steering committee on behalf of the minor-plaintiffs suffering from birth defects who have filed claims. If you or a loved one took Zofran during the first trimester of a pregnancy and the child was born with any of the following congenital heart defects or cleft palate, you could be entitled to compensation:

  • Ventricular Septal heart defect (VSD)
  • Atrial Septal heart defect (ASD)
  • Hypoplastic left heart syndrome (HLHS)
  • Pulmonary atresia (PA)
  • Tetralogy of Fallot (TOF)
  • Tricuspid Atresia (TA)
  • Total anomalous pulmonary venous return (TAPV or TAPVR)
  • Transposition of the great arteries (TGA)
  • Cleft palate

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Securities Lawyer Melissa_Hague

Melissa Fry Hague

If you believe you or a loved one may have a Zofran claim, contact us today. One of our attorneys will contact you within 24 hours to conduct a free and confidential evaluation of your case.